Respiratory complications are the leading cause of morbidity and mortality in patients with CF. Thick mucus blocks the airways in the lungs leading to inflammation and recurrent infections. With each infection, more damage or scarring occurs causing lung function to progressively worsen. This is why regular, routine treatment is so very important to keep secretions cleared and prevent infection . Routine treatment is usually performed 2 times a daily for maintenance. An increase in cough is usually the first sign of infection and worsening inflammation. Automatically increase CPT therapy to 3-4 times daily and contact your CF center for further instructions. With good, routine treatment, the decline of pulmonary function can be slowed and the lungs kept healthy for long periods of time. Various airway clearance techniques and aerosol therapy will be prescribed to assist in clearing retained secretions from the lungs.