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A cluster of genes close to one another at a chromosome locus are called contiguous. Contiguous gene disorders result from deletions or duplications of a chromosome segment that cause a contiguous gene imbalance. Also, Contiguity refers to the way Taxonomy is ordered and formed after Charles Darwin wrote Theory of the Origins of Species in 1859. Before then, scientists used a more strict taxonomy based upon an organism's locomotion and mobility. Now science bases taxonomy on contiguity, tracking changes in an organism's anatomy over eons to show contiguous shaping over time.